Contents: Scope and magnitude of the problem / Bryan Jennett-- Metabolic and physiologic changes in acute brain failure / Stig Rehncrona and Bo K. Siesjö -- Ischemic brain injuries / Julio H. Garcia and Karl A. Conger -- Clinical evaluation of acute brain failure / John F. Caronna -- Advance monitoring of the brain / Richard P. Greenberg ... [et al.] -- Radiology of brain failure / Robert A. Zimmerman -- Cerebral blood flow measurements in the critically ill patient / Michael M. Todd, Harvey M. Shapiro and Walter D. Obrist -- Resuscitation after brain ischemia / Peter Safar -- Head trauma and intracranial hemorrhage / Graham Teasdale and Samuel Gelbraith -- Neuroanesthetic-pharmacologic considerations / Philippa Newfield and James E. Cottrell -- Decision-making in brain death and vegetative states / David F. Powner, Rosa Lynn Pinkus and Ake Grenvik.